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Glutathione dapat menghilangkan molekul-molekul berbahaya ini, mengurangi kerusakan DNA, dan mendukung mekanisme perbaikan intraseluler untuk menjaga stabilitas gen

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Clinical trial protocols begin with a 0.3 mg starting dose as a titration starting point, escalating gradually toward higher investigational targets over approximately 16 weeks

Abbreviations [Ca 2+ ] i : Intracellular Ca 2+ concentration ER: Endoplasmic reticulum GCG: Glucagon GCGR: Glucagon receptor GIP: Glucose-dependent insulinotropic polypeptide GIPR: Glucose-dependent insulinotropic polypeptide receptor GLP-1: Glucagon-like peptide-1 GLP-1R: Glucagon-like peptide-1 receptor GSIS: Glucose-stimulated insulin secretion HFD: High-fat diet LFD: Normal chow diet KO: Knockout nt: Nucleotide PKC: Protein kinase C PLC: Phospholipase C TPPO: Triphenylphosphine oxide TRPM5: Transient receptor potential melastatin 5 WT: Wild-type References Finan B, Yang B, Ottaway N et al (2015) A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents